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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCLK1
All Species:
19.7
Human Site:
S294
Identified Species:
39.39
UniProt:
O15075
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15075
NP_004725.1
740
82224
S294
I
A
S
S
S
R
R
S
T
T
K
S
P
G
P
Chimpanzee
Pan troglodytes
XP_522657
872
96662
S437
I
A
S
S
S
R
R
S
T
T
K
S
P
G
P
Rhesus Macaque
Macaca mulatta
XP_001082020
783
85228
S315
S
P
G
P
S
R
R
S
K
S
P
A
S
V
K
Dog
Lupus familis
XP_849124
740
82175
S294
I
A
S
S
S
R
R
S
A
T
K
S
P
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLM8
756
84135
G294
I
A
S
A
S
R
R
G
T
T
K
S
P
G
P
Rat
Rattus norvegicus
Q5MPA9
767
83998
R313
R
S
P
G
L
S
R
R
S
K
S
P
A
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511397
792
88039
S355
I
A
S
T
S
R
R
S
T
T
K
S
P
G
P
Chicken
Gallus gallus
XP_417099
1048
115422
S600
I
A
S
S
S
R
R
S
T
T
K
S
P
G
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q501V0
422
47914
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7PLI7
748
82953
G281
L
K
N
G
L
L
A
G
S
S
P
F
P
A
C
Honey Bee
Apis mellifera
XP_394386
670
74883
G250
D
D
I
F
V
A
Y
G
P
E
K
S
N
Q
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189418
661
74296
I242
Y
T
L
D
G
R
Q
I
H
S
L
Q
G
F
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.4
65.3
99.8
N.A.
96.4
65.3
N.A.
86.2
63.7
N.A.
24.7
N.A.
29.8
41
N.A.
52.3
Protein Similarity:
100
80.1
77.5
99.8
N.A.
97.3
77.8
N.A.
88
64.9
N.A.
35
N.A.
47.5
57.9
N.A.
65.9
P-Site Identity:
100
100
26.6
93.3
N.A.
86.6
6.6
N.A.
93.3
100
N.A.
0
N.A.
6.6
13.3
N.A.
6.6
P-Site Similarity:
100
100
40
93.3
N.A.
93.3
20
N.A.
100
100
N.A.
0
N.A.
33.3
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
50
0
9
0
9
9
0
9
0
0
9
9
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
9
9
0
9
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
0
9
0
9
9
% F
% Gly:
0
0
9
17
9
0
0
25
0
0
0
0
9
50
0
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
50
0
9
0
0
0
0
9
0
0
0
0
0
0
0
% I
% Lys:
0
9
0
0
0
0
0
0
9
9
59
0
0
0
9
% K
% Leu:
9
0
9
0
17
9
0
0
0
0
9
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
0
9
9
9
0
0
0
0
9
0
17
9
59
0
50
% P
% Gln:
0
0
0
0
0
0
9
0
0
0
0
9
0
9
0
% Q
% Arg:
9
0
0
0
0
67
67
9
0
0
0
0
0
0
0
% R
% Ser:
9
9
50
34
59
9
0
50
17
25
9
59
9
9
0
% S
% Thr:
0
9
0
9
0
0
0
0
42
50
0
0
0
0
0
% T
% Val:
0
0
0
0
9
0
0
0
0
0
0
0
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _